Switching from Efavirenz Does Not Improve Cognitive Function

Despite effective antiretroviral therapy (ART), mild cognitive impairment (things like decreased attention span, poorer memory, worse problem-solving ability) remains common in people living with HIV. The reasons for this are poorly understood and little is known about the impact of specific anti-HIV drugs on neurological function. However, efavirenz – one of the most commonly used antiretrovirals […]

Life Expectancy Near Normal

A large study of 88,504 people with HIV on antiretroviral therapy (ART), published in the Lancet journal and reported widely in the news, has found substantial improvements in life expectancy in people with HIV who started ART after 2008, even in their first year of therapy. People who started ART in 2008-2010 and who had […]

HCV Transmission in MSM

HCV is primarily a blood borne infection, so sex that includes blood-to-blood has the highest risk. In MSM, this has led to the view that the risk of transmission is high when using sex toys, fisting, “slamming”, chemsex, and “rough sex”. Although HCV has been found in semen, and also in vaginal fluid, until now […]

Generic HIV Drugs

The financial pressures faced by HIV clinics in the NHS was a major theme of the recent British HIV Association conference. Doctors discussed how they can keep costs down without compromising the quality of care. One of the most important ways they can do so is to switch some patients from branded, expensive drugs to […]

Co-infection with HCV increases cancer risk for people with HIV

As a result of highly-active antiretroviral therapy (HAART), many people with HIV now have a near-normal life expectancy. However, rates of serious non-HIV-related illnesses are higher among people with HIV compared to individuals in the general population. Several studies have shown that even for people taking effective HAART, they have higher risk of several malignancies not traditionally associated […]

New version of Tenofovir

Tenofovir disoproxil fumarate (TDF) is one of the most widely used antiretroviral drugs. It is highly effective in treating HIV,and for most people, generally safe and well-tolerated. However, in a small minority of cases it can cause kidney problems. And TDF has an impact on bones…for most people, this is small and not noticeable, but […]