A poor CD4 response to antiretroviral therapy (ART) is associated with an increased risk of virus-related non-AIDS-defining cancers (NADC), US investigators report inĀ AIDS. The authors recommend that people living with HIV who have low CD4 counts should be intensively screened for virus-related malignancies. The most frequently-occurring virus-related malignancies are those caused by human papilloma virus (anal cancer and squamous cell cancers of the oral cavity and pharynx), hepatitis B and C (liver cancer) and Epstein-Barr virus (EBV, Hodgkin lymphoma).

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