A large international study has provided persuasive evidence of the long-term safety of antiretroviral therapy.

It is now well recognised that effective antiretroviral therapy has significantly improved the life expectancy of many patients with HIV. However, HIV ARV drugs can cause side-effects, and treatment with some specific drugs has been linked to an increased risk of cardiovascular disease or kidney dysfunction. This raised the concern that prolonged treatment with antiretroviral therapy might carry an increased risk of death from these or other non-AIDS diseases.

This study suggests that prolonged use of antiretroviral therapy did not increase the risk of death from non-AIDS-related illnesses.

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