Adherence – taking your ARV drugs on time, every time – is a key part of HAART. Poor adherence can lead to drug resistance, and complicate¬†future therapy. This article looks at different patterns of poor adherence, and finds that missing the occasional single dose is less harmful than taking an unplanned or unstructured “drug holiday” – not taking any ARVs for a prolonged period. This is perhaps not too surprising.¬†Modern ARVs are generally more “forgiving” than older ARVs, so missing the odd dose infrequently is unlikely to be a serious problem; however, it is certainly best to aim for full adherence wherever possible.

The full article can be seen here.