With the right treatment and care, the outlook for most people living with HIV is excellent. However, there is a decrease seen in bone mineral density in patients with HIV. The exact causes are uncertain, but may include the HIV infection itself or the effects of antiretroviral therapy. Some studies have shown that patients taking HIV treatment have an increased risk of fragility fractures, but such findings have been contradicted by other research.
A recent large, long-term study in the US has now suggested that the risk of fractures is overall reduced for people living with HIV if they are on ant-retroviral treatment (ART) as opposed to those not on treatment. The inter-relationship with specific ART drugs is more complex, but with regard to the risk of fractures, being on treatment is better than not being on treatment.
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