As people age, they typically take a growing number of medications to treat chronic conditions. The impact of polypharmacy (taking lots of different drugs at the same time) is receiving increasing attention in HIV populations, who already usually take three or more antiretrovirals that may interact not only with each other but also with non-antiretrovirals. A recent US study looked into this and found that every 10 years of age independently raised the chance that a person living with HIV would be prescribed an antiretroviral and a non-antiretroviral that should not be given together. One third of those in the study were prescribed medications with moderate or high evidence of a possible drug-drug interaction. When someone taking ARV therapy is prescribed drugs for another condition, the clinician should always check to ensure that there are no drug-drug interactions.
The full article can be read here.